Tuesday, August 25, 2009

Lightning helps create artificial blood vessels




Lightning bolts could help create artificial organs, according to new research by scientists at Texas A&M University.

An electrically charged block of plastic gives way to a series of tunnel-carving lightning bolts when a nail is driven into it. Adding human blood vessel cells to the tunnels could create a template upon which an artificial organ could grow.

"One of the biggest problems in tissue engineering is how to create a vascular network to feed the growing tissue," said Arul Jayaraman, a professor at Texas A&M who, along with his colleague Victor Ugaz, co-authored the study that appears in the journal Advanced Materials. "The structure of these networks closely resembles the human vasculature."

The artificial organs begin as clear blocks of biodegradable plastic about the size of an inch-thick stack of Post-It notes. An electron beam fills the block with electricity, then the scientists drive nails into either end of the plastic block.

With each strike of the hammer, lightning streaks through the block and exits through the nail, leaving tiny tunnels in its wake. "It's pretty spectacular," said Jayaraman. "It looks just like lightning bolts."

These tunnels are remarkably similar to the capillary system inside the human body. At their largest size, where the nails are driven in, the lightning induced tunnels are about the same size as veins and arteries. In the middle of the block, the tunnels are smaller, about the same size as capillaries.

The tunnels also connect with each other; fluid that goes in one side comes out the other. The streaking of the lightning might seem random, but it penetrates all areas of the block, ensuring an adequate blood supply to the entire organ.

The entire process takes only a few seconds. That's much faster and cheaper than previous efforts to create 3D artificial channels, said the researchers.

Veel: http://www.msnbc.msn.com/id/32509657/ns/technology_and_science-science/

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